Simulation of Mathematical Modeling of Malaria with Vaccination

Objectives General Objectives. To formulate and analyse malaria with vaccination. Specific Formulation of model Estimation parameters Numerical solution clarify the importance vaccination through discussion. Methodology: We build a flowchart diagram. simulate data which helps to find parameter values that makes fit in order verify validity or adequacy model. use least squares method estimate interpretation it. analyze by computing basic reproduction number R0, disease-free equilibrium point endemic point. And also discuss behavior numerical solution. solve numerically using MATLAB software. solutions are presented graphical way allows visualize predictions. Results: Model has shown rates reduce number, means involved eradicating from population. control spread disease, we introduced herd immunity strategy is concerned about immunizing large people population take protective measures for rest including children pregnancy women. Thus, calculated threshold 0.0517, this value 5.17% susceptible be immunized plasmodium parasite. Our was fitted simulated implies can used transmission predict mechanism prevention vaccination, it involves eliminating malaria. Unique contribution: Malaria an infectious disease become very common becoming more widespread uncontrolled throughout Africa, as well whole world, due bite female anopheles’ mosquito spreads plasmodium. In attempt eradicate deadly massive response needs mounted governments enlighten public prevalence provide remedy treatment On issue, over last few decades there have been millions dollars much efforts put into fight against Plasmodium falciparum but unfortunately still no registered vaccine Is best peoples dying malaria? Many researchers worked on different they did not introduce my Introduce see if strategies